Endocrine Abstracts

Chronic stress, low socioeconomic status and ingestion of hypercaloric food are all recognized risk factors for obesity, metabolic syndrome (MetS) and type 2 diabetes (T2D). Given the complexity of these metabolic processes and the unavailability of animal models, there is poor understanding of their underlying mechanisms. We established a model of chronic psychosocial stress (CPS) in which animals of low social rank (subordinates, SUB) are vulnerable to weight gain while anim...